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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7563103542fc55fc6b67f6238ead8dc6c978e0264e17f3fd4399034e3528f28c' 
  AND token = 'oZ5gk4Nbq0JP1m/kj4aZSaPd8TT/pV5MigYr+R1XOcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}