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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '638f45a49a28ecc13a5b63c15ef8946f9aad06f133d288f7f6b3ce8c6cb9f593' 
  AND token = '6ObU9clLzb4I3WmjmEJ/rGbPNciTuNEbTK+/ZcBjruU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}