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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8481cb1d7999cba0068ad1a147a75d0d264b3fa9a8e7ecfdf6407b5d99615560' 
  AND token = 'BkIre1FsWr5837WGez9I23SvKYvDHMqB8wiffueNktw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}