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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '410cb81ccc63e5dc5331d3e12949d288585884de971cf365d3955b0d072b203f' 
  AND token = 'L+21P+Fq+vop3ETVoswkNjJwTjlqOf5o1fkIi8VfZWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}