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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b81e97fa081193c758fd0227090089292280d57cc83685a4dfb736afbfbb0ff5' 
  AND token = 'cC5J5yENm6SLSeXsCVyQU4VNsJgzsTaWBMvRWmv18DI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}