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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e2b13104279da9b2fd8bde3890dcd3271147f5ca9b3a327bfa0bb1bc2eb3b45' 
  AND token = 'gWZYRd0s7lob7TqGfQit3RrOG/d/YGqd3LcFau4IKgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}