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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de6780b84dfebb197e3ce8f43855d7dd25c5fee3990f4bddbd472d5daabfc7c1' 
  AND token = '4L1ttY1WMHS/qwZ4uSBgYw8f+T3JBE+58KYYgTGUuSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}