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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5f6612591ae76d764e7de3a4ae071b03581d5485d567f27ceeb608d06de4a52' 
  AND token = 'rZWaO9ZjG+1v0jA/c4qvCw9/oDTcsD0zipdIr+r4YQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}