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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4c1b90b0f04c806f6b7fa74d777c5b6934109a415d77c3a3841f2a963feefe2' 
  AND token = '3+KIb9vzQV54v/RPepnGmM1o145U7aeHlEc1Ndd3MMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}