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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18172431298665fb4a8c68caa7649d08acb3e62cd619b2dd8da9ac7a63c8442b' 
  AND token = 'B3mKkZW0GYS1om/wZEHUCbHvbwUbDiwMiN7t3MpPD9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}