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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '622852c2fe85b19a7020f73e1faf0831ec85a45306b0c95dce4c0f5c0701e564' 
  AND token = 'TX1VNlFmPPMvCGleKG5/5VlUW7DSzEpv9FGTgpzI/Bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}