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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40838ebfdf1574ac83fc05a19e9e1fae15bb09d3a348b183eebe9434f7dcdb88' 
  AND token = 'y2gDc7Q/z1abCnEEij4GAGaW7rr4hMx4RZ+pPWk8Cm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}