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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e000d02b1c7f46dfebb452a32c39b1b898ce34e21d0a2a0a670122e7ff721b6f' 
  AND token = 'nRMbnQOxoqml7qILQk8DinItZQ8Jrvvk5/GnbquC8Xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}