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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39f21840004e954f9144015d3e0304fc8c10bf062d0ac747af4e71f429347724' 
  AND token = 'o08+70YrYmYlh7kzSIUxlUIAtGBp4WwPP65ibymPHEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}