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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '295ec01326559f84de4d0c9b46e05264ed473cd89817ea265a79e9a8dd1f5da3' 
  AND token = 'Ct/r125Gz5+Tt1TkmsnGolx8k3IfKB6WHb1dc7VFzWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}