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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccdbec4180b88c789b9b4bf77de425f2ab9c374e18763ab2d106c9617d906bad' 
  AND token = 'GP0C56CtpIN4EI1DOYKZQKMUbhk20AkaFM0tr+MjZ7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}