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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72432d7f9ba9747b88815fc99a6bb12b947d0d39bbd9255dc1ccc01b34bcac49' 
  AND token = 'QReqxMVY0VHkE5ZPmIw/N+7pkwbK6TS2UWzUYh92Jd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}