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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39dd3dee12cd31df8dd74f3649d8c5a03b418cc86441fd65d208f7e365f0247f' 
  AND token = 'EHV24XGhAf6EBupr2i2N9eGiFgXHpbmJYyYYaY2eESw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}