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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4b680982d6412d9d7249d59d730b1bada54ca13c7628c61d0bb70c9829723b7' 
  AND token = 'awF+WgTLRHxU1TYo7xfPVsNQg/5u7xNgjwgll9xoeOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}