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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '581a5bf7c6b53c8e70740fb666aaa2d3cd1bb588a4ad0b4098c36a2c82b334d1' 
  AND token = 'QvR/oqlcJEK4n3qfk5c40BGiULlZBD33TJrwdcSUbRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}