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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8ecaab46527eeeddd3fd6382dd8e0559720c1623d6630f3b765f960175eb8c1' 
  AND token = 'VpAY/K8JVZpf9JOTk3bLoCns+TnSAIZQnZ1zqFpi8es=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}