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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1efc86c4629ec5276eec7061b5131f23778ddb6552e071621fbf453e0d8e3411' 
  AND token = '5TrOpyiAb7QVk6cijqoA+QAiA+v2leZURxNKyM/h3+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}