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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fa8223ecb79b80edac3abe486536522cf7410f55f47ed5c23147f24c6224248' 
  AND token = 'SC1UXKXlKO0PkiEsgkjY7T8ma77Kv2GRo9CpoNqU/Ac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}