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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb4a3c4a19736b46425f1514442afbddd635f2fa67b51cef3048031c3e63314a' 
  AND token = 'swS4rygjLlhEJk1gwIASNhFxiHvxSN/a+xLC9NDOuic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}