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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ecc220fe4106ce8a05dea86451960f5c5f890ba115db2ac8db091b0e4e151ca' 
  AND token = 'hvWtETYwkqna5pU9jMOi1hW9dwe/oFbXa6XGZbWJFu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}