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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de6ad20a80813ce980104b7ab251807167944ebd8d9b0a96927e72e9a9cc8833' 
  AND token = 'nylW7/VArhcDrvJy+27jU8NAYT5/jvV06LGbKeL8tQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}