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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6000556cc9713e4207bf8e27127b6618b79422b953cd026de1d79882665665ea' 
  AND token = 'Rfp5e6GvMOwNJ4MQ10W6a4lyUJyKBju5bRiF+3dtW9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}