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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3389f85f9915886a79a1d4419ce9f21ebbc041b20fe966e9e73b66dc1d389ba6' 
  AND token = '8oTuFk46JNle+IAPlF7w0a97Ev6TnCJrSm0xzFHv4cY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}