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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b1dd607ded6c0a292ceb60a4e86559e392ebf266af423b8c9fef866a528afa4' 
  AND token = 't4E1K2Mayj0xLu1W7OAy/7w3xCa2uMcnIB20orkM5J8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}