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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71253befa4cbb20318a52b8353d521baef1a0f20bf9c4c699e9d6253be6e05fc' 
  AND token = 'Gw7ET0Rp6o54P+v6xfsMlhDyZ36ygHh+owWWC0icijg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}