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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21b64855579ba5dbd38ec469ba9e7f9e121b82451701e8b316c4d30172209a5c' 
  AND token = 'Ftgs+vTXIvjNGlr9ZHP3BOdi2BtE6O55LHVXam6evJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}