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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff67aad317508fb4e62c030f4e698d0a25fc2dcac6aea43e912f782f0e244207' 
  AND token = 'ucA9W1tR+pIk1nNQgoHSdawXzBE+Z8eFbJL6tjqURZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}