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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e76b5a6629c58210e167da774b42e4ad597473f191c0ba9c1bdb6df1e097436f' 
  AND token = 'cBIo0r9tQkZcMj8lxhYbzfEw72OQ9mCtEcdr51A6Vg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}