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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6b43e958338770578f5fcb89ad59e6efc8d284515580c73caff1e2f49276aba' 
  AND token = 'rW8s+xZ6j0FVsmNt1EvitC4S3bvTyq0GMEw4eDd6U9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}