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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1383d05deacbc7d1585f16c800c794158f273d32b77e33041e4f84d7695d8f2f' 
  AND token = 'TXGwbCcYUoQcCa/0YAgf8iMfzcxDY2TzZhTBg8n0Q4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}