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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c5d7d7fc21c269e8547276123c4bfddfe65deee73ab2ad835b3873fd0c614ba' 
  AND token = 'lIDx2taXn0jW/y8CJAzyfo9Y0PUuhQGZHENt+at4hMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}