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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d1b481de2feb95de8d56a1d0e6be8ec214d96219e1c759b88020b5e78ca4041' 
  AND token = 'FpBxbPFuVd0LU+QQ3q4R2ET7v/Oe7t4koI6apMvz4tI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}