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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cba58a13d7e2f43b0fbf830122ccedd2109f664d352ce2e848e92b331168973' 
  AND token = 'h1Py3vuou2xqQ4l8BfKtn0apj09QOXPKuqcWKCRKydo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}