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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b8489334fe11053e378709a7ec11391263e23dc25d0ad1bc5a7564d9c474246' 
  AND token = 'Vo3rUhuL+iU2Q3n1xwzVmQpJYgd1vzyI0LuTcsquSCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}