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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c53a30bd5f456e2e8a165c425242a421c92ea8eccf643477aabe814871b6995f' 
  AND token = 'CL19MPx12WhfYKfl4CRcqe1QUqE1Ohj0eC/12P7Lie8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}