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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd80ad3df48d33ad2cdfb084473a22d0c3c7c45a8280d842b88074af1f2ab164d' 
  AND token = '7SzavZb00VvwfTGKY9+lgHm2lEwwZssB7Re0IYOk3y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}