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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bfba13a68fb27a7db5d6e187330dce8b6635df5b83e050be2747407450af234' 
  AND token = 'bxqAeWsTEs7aKKFVaSyYfxPhrGheqrpKXhrDpfPCMHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}