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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e28d8b99b9e35631457ac1cfa46a09f307d8d49516011fd3f1d798a8cb51c5c2' 
  AND token = 'DQupI+zIFrrd6XbSWWE+4l8V1YIwzTtcmJyQGA+jWUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}