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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c1081e9e99f8886f611e4dea7d4a4065679195c88056b2e98011a586379ea94' 
  AND token = 'ADKF/SHla2luqGl34tTcd4t+Vh+p9o4sQyWNSyEbzlI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}