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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fb4c5ed1a44ac5a603d5314020aa12cbaa2e037a5453fd292d8afbe0502b023' 
  AND token = 'vwJUkdguTvlP+8JiemCdf8VwM9DO+a+mPk1l6vUKfSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}