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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6af4e21834c0b6c3772d21103d2838d0c7677e5ecb55a4d0f922187125c1bb49' 
  AND token = 'CSfkxhfwmTuD2i2JHgZth4iZCsSp4xZsqqp+77OFNY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}