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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50e279657ab7595885451d023879b5b2d98b13092606a7f341af8795981596c2' 
  AND token = 'SrwXb2D5ufYdnv1DjgQhoZiBOL0G5lTN1C84x+f6Zsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}