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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77f7a70c39224bddc04f6d46dd54eaa3e9347bc64c773ac82c5485fd9fbeba7b' 
  AND token = 'Z4qbPTSdwXt9zfBRJ0fNWssEmLA8HmT7Z7eKHl+sdAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}