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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '289fc567a7283b4a9d3cfe60782813b7cfd0929fbce1c6e861cc0e9d36c1c39d' 
  AND token = 'Dr7WNjo9EuEBGsm39UlcLdA2F7xnGh+nDne2ovciHWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}