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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f54a1e080d0708ac00d321d1c2c1aa834ee050b2b2ba2205693dc7e0d283b06' 
  AND token = 'DUnIU1Q9AekhA3aHtWm2FM1OIckQFkokGBWZJKikhnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}